Conquer Your Gut: A Guide to SIBO Treatment Options

SIBO, or Small Intestinal Bacterial Overgrowth, can leave you feeling bloated, gassy, and straight out miserable. But don't despair! That was me too and I am here to tell you the facts, and let you know that there is hope. This comprehensive guide explores the most common and effective SIBO treatments, empowering you to make informed decisions about your journey towards good gut health. If you’re not sure what SIBO is, make sure to read my article on SIBO 101 first.

By the way, I have tried all of the following categories myself (my poor gut😭) and am still well and alive; I just wished I knew better back in the days, and can now report back on them.

1. Antibiotics: The “Heavy” Hitters

While antibiotics are frequently used to treat SIBO in conventional medicine, they are not always the ideal solution for everyone. Some of them target specific bacteria, while others are more broad-spectrum, meaning they will kill both “good” and “bad” bacteria in the process. Commonly prescribed antibiotics for SIBO (which have been studied) include:

  • Rifaximin (Xifaxan): This antibiotic is specifically designed to target bacteria in the small intestine and is generally well-tolerated. It mainly works on hydrogen gas producers. The downside is that it can be very expensive, especially if your insurance won’t cover it. There are ways around this if you are crafty, however. If you need more info, you can contact me here.

  • Neomycin: This antibiotic is effective against a wider range of bacteria, but it can have more serious side effects. It is often required for mixed SIBO (where both hydrogen and Methane are elevated) or in cases of Intestinal Methanogen Overgrowth (IMO). It can also be harder to access in some countries and compounding may be necessary.

  • Metronidazole (Flagyl): This antibiotic is usually used when Neomycin is unavailable, and is effective against certain types of bacteria. It can also have side effects like nausea and metallic taste.

All in all, rifaximin is the safest antibiotic of them all and the least likely to cause issues and further dysbiosis. I do not prescribe medication myself but have worked with clients desiring to go down the antibiotics’ route. It is personally not my preferred option, but depending on the cases they can be helpful or the right option.

2. Antimicrobial Herbs: Nature's Allies

Some individuals (myself included) might prefer a more natural approach. Antimicrobial herbs can help to combat SIBO by inhibiting bacterial growth and promoting a healthy gut environment. The key thing to know here, is that antimicrobials herbs can be VERY potent, and show also be used with some caution. Some herbs are broad spectrum and can cause as much damage on the microbiome as some antibiotics. So just keep that in mind before embarking on a DIY protocol you found online. Some popular options include:

  • Berberine: This potent compound has antimicrobial properties and can help reduce inflammation in the gut. It is found in herbs such as Coptis, Barberry, Oregon grape or Goldenseal.
    You can also find it under Berberine HCL. Berberine is definitely not for everyone and can lower blood sugar to dangerous levels in some individuals. I have a full article on Berberine for SIBO.

  • Oregano oil: This oil contains carvacrol, a powerful antimicrobial compound. I have a full article on oil of oregano for SIBO.

  • Garlic: Garlic contains allicin, a natural antibiotic that can help fight SIBO. I also have a full article on allicin, here.

  • Clove: Clove contains eugenol, an antimicrobial agent that can help combat SIBO.

  • Pomegranate: Pomegranate contains punicalagin, a powerful antioxidant with antimicrobial properties. This one is commonly used in Australia, but harder to find in other countries.

  • Neem: Neem has been traditionally used for its antimicrobial and antifungal properties.

  • Wormwood: Wormwood contains artemisinin, a compound with antimicrobial activity.

  • Thyme: Thyme contains thymol, an antimicrobial agent that can help fight SIBO.

Important Note: SIBO treatment often involves a blend of two or more herbs, depending on the type of SIBO and its severity. Whether you have Hydrogen dominant (H2) SIBO, Methane SIBO (IMO) or Hydrogen Sulfide SIBO (H2S), herbal options will vary. Working with a SIBO practitioner is highly recommended to create a personalized herbal blend tailored to your specific needs.

3. The Elemental Diet: A Reset Button

The elemental diet is a short-term, highly restrictive diet that provides all the essential nutrients your body needs in a pre-digested form. This eliminates the need for the gut to break down food, allowing the small intestine to rest and heal. It is often used as a treatment for severe SIBO cases. It can be very effective if followed correctly. It will likely not affect any imbalance in the large intestine, however, due to its mechanism of action. I have an article on the Elemental Diet for SIBO here.

4. Motility Matters: Getting Things Moving

SIBO can occur when the small intestine's natural motility (movement) is impaired, allowing bacteria to overgrow. Addressing motility issues can be a crucial part of SIBO treatment.

  • Bile Output: Bile, produced by the liver, plays a vital role in digestion and helps to control bacterial growth in the small intestine. If bile production or flow is compromised, it can contribute to SIBO.

  • Probiotics: Probiotics introduce beneficial bacteria to the gut, and specific strains can help to improve motility and rebalance the microbiome.

  • Lifestyle Changes: Regular gentle exercise, stress management, and adequate hydration can all support healthy gut motility.

  • Prokinetics: Prokinetics help to speed up the movement of food through the digestive tract. They can be helpful in cases of SIBO where slow motility is a contributing factor. There are some good pharmaceuticals and herbal options. I will make an article on prokinetics in the future so stay tuned!

Note that in some mild cases, antimicrobials or antibiotics might not be necessary when motility is addressed and digestive function is working optimally. By digestive function I include: digestive enzymes output, appropriate stomach acid levels and proper bile flow.

5. Rebalancing the Microbiome: A Holistic Approach

SIBO is often linked to an imbalance in the gut microbiome. Restoring a healthy balance of bacteria can be crucial for long-term SIBO management. Is it also important to consider that in some cases, the imbalance is more present in the large intestine (colon) rather than the small intestine. This is sometimes referred to as LIBO. In such cases, antibiotics and antimicrobials might not be necessary.

  • Prebiotics: Prebiotics are types of fiber that feed the beneficial bacteria in your gut, helping them to thrive.

  • Probiotics: Probiotics introduce beneficial bacteria to the gut, helping to crowd out harmful bacteria and restore balance.

  • Diet: A balanced and varied diet rich in fruits, vegetables, and polyphenols supports a healthy microbiome. Please read my article on carnivore diet for SIBO first if this is something you are considering.

Important Considerations:

  • SIBO is unique to each individual: What works for one person may not work for another. It's crucial to work with a SIBO or Gut Health Practitioner to determine the best treatment plan for you.

  • Lifestyle factors play a role: Stress, lack of sleep, and poor diet can all contribute to SIBO. Addressing these factors is an important foundation to start with for long-term success.

  • Treatment is often a journey: SIBO treatment may require a combination of approaches and can take time to see results. Be patient and persistent in your efforts! It took me three years, but I also did a lot of mistakes (which thankfully I have learned from)!

Remember: This blog post is for informational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment plan.

By understanding the various treatment options available, you can work with a practitioner to create a personalized plan that addresses your unique needs and helps you reclaim your gut health!

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Carnivore Diet for SIBO: A Temporary Fix or Long-Term Solution?